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These data come from Cosmos, a dataset created in collaboration with a community of Epic health systems representing more than 300 million patient records from 1,700 hospitals and more than 40,000 clinics from all 50 U.S
Following peripheral administration, exenatide has been shown to suppress food intake via vagal-dependent and vagal-independent pathways that result in the direct activation of GLP-1R in the central nervous system
ATP-binding cassette (ABC) transporters (e.g., P-glycoprotein/MDR1, BCRP/ABCG2) actively expel hydrophobic chemotherapeutic drugs from the cell, thereby reducing the intracellular concentration of the active drug
pores, removing residue gently and thoroughly
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